Lancet - Vit K Antagonist Reversal

"Four-factor prothrombin complex concentrate versus plasma for rapid vitamin K antagonist reversal in patients needing urgent surgical or invasive interventions:"

"Interpretation

4F-PCC is non-inferior and superior to plasma for rapid INR reversal and effective haemostasis in patients needing VKA reversal for urgent surgical or invasive procedures."

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(14)61685-8/abstract