Sunday, May 1, 2016

Research May 2016

ANNALS

"Gradual Versus Abrupt Smoking Cessation: A Randomized, Controlled Noninferiority Trial"
http://annals.org/article.aspx?articleid=2501853

"Long-Term Risk for Device-Related Complications and Reoperations After Implantable Cardioverter-Defibrillator Implantation"
http://annals.org/article.aspx?articleid=2520465

BMJ

"BMI and all cause mortality: systematic review and non-linear dose-response meta-analysis of 230 cohort studies with 3.74 million deaths among 30.3 million participants"
http://www.bmj.com/content/353/bmj.i2156

"Effect of age and sex on efficacy and tolerability of β blockers in patients with heart failure with reduced ejection fraction: individual patient data meta-analysis"
"Conclusion
Irrespective of age or sex, patients with HFrEF in sinus rhythm should receive β blockers to reduce the risk of death and admission to hospital."
http://www.bmj.com/content/353/bmj.i1855


CIRC / JACC
"Reduced Cardiac Index Is Not the Dominant Driver of Renal Dysfunction in Heart Failure"
http://content.onlinejacc.org/article.aspx?articleID=2520902

 
"Diabetes Mellitus and Prevention of Late Myocardial Infarction After Coronary Stenting in the Randomized Dual Antiplatelet Therapy Study"
http://circ.ahajournals.org/content/133/18/1772.full


JAMA  
"Effect of Using the Same vs Different Order for Second Readings of Screening Mammograms on Rates of Breast Cancer Detection"
 "Conclusions and Relevance  Interpretation of batches of mammograms by qualified screening mammography readers using a different order vs the same order for the second reading resulted in no significant difference in rates of detection of breast cancer."
http://jama.jamanetwork.com/article.aspx?articleid=2520628 
 

"Prevalence of Inappropriate Antibiotic Prescriptions Among US Ambulatory Care Visits, 2010-2011"
http://jama.jamanetwork.com/article.aspx?articleid=2518263


NEJM
"Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest"
http://www.nejm.org/doi/full/10.1056/NEJMoa1514204?query=featured_home

"Initiation Strategies for Renal-Replacement Therapy in the Intensive Care Unit'
http://www.nejm.org/doi/full/10.1056/NEJMoa1603017?query=featured_home


Guidelines May 2016

May 26, 2016
"2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease"
http://circ.ahajournals.org/content/early/2016/03/28/CIR.0000000000000404

"Duration of Dual Antiplatelet Therapy: A Systematic Review for the 2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease"
http://circ.ahajournals.org/content/early/2016/03/28/CIR.0000000000000405
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May 19, 2016
"Appropriate Antibiotic Use for Acute Respiratory Tract Infection in Adults: Advice for High-Value Care From the American College of Physicians and the Centers for Disease Control and Prevention"
http://annals.org/article.aspx?articleid=2481815
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May 12, 2016
"Aspirin Use for the Primary Prevention of Cardiovascular Disease and Colorectal Cancer: U.S. Preventive Services Task Force Recommendation Statement"
http://annals.org/article.aspx?articleid=2513179

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May 5, 2016
"AHA Scientific Statement Electrocardiographic Early Repolarization"
http://circ.ahajournals.org/content/133/15/1520.full

"The early repolarization (ER) pattern (ERP), initially described as elevation of the ST segment of ≥1 leads on the 12-lead ECG, has long been considered a benign phenomenon. However, more recent studies have demonstrated positive, negative, and neutral associations between an ERP and various end points, including all-cause, cardiac, and arrhythmic mortality. These recent studies have used more complex or heterogeneous definitions of ER, including J-wave or J-point elevation and QRS complex notching or slurring, with or without concomitant ST-segment elevation. Other studies have identified an increased prevalence of ERP in survivors of spontaneous ventricular fibrillation (VF) or cardiac arrest."