"The Natural History of Benign Thyroid Nodules"
"Conclusions and Relevance Among patients with asymptomatic, sonographically or cytologically benign thyroid nodules, the majority of nodules exhibited no significant size increase during 5 years of follow-up and thyroid cancer was rare. These findings support consideration of revision of current guideline recommendations for follow-up of asymptomatic thyroid nodules."
http://jama.jamanetwork.com/article.aspx?articleid=2174027
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