Tuesday, December 2, 2014

NEJM - Ebola Vaccine

"Chimpanzee Adenovirus Vector Ebola Vaccine — Preliminary Report"

"CONCLUSIONS
Reactogenicity and immune responses to cAd3-EBO vaccine were dose-dependent. At the 2×1011 particle-unit dose, glycoprotein Zaire–specific antibody responses were in the range reported to be associated with vaccine-induced protective immunity in challenge studies involving nonhuman primates. Clinical trials assessing cAd3-EBO are ongoing. (Funded by the Intramural Research Program of the National Institutes of Health; VRC 207 ClinicalTrials.gov number,NCT02231866.)" 

http://www.nejm.org/doi/full/10.1056/NEJMoa1410863?query=featured_home

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