Wednesday, September 10, 2014

BMJ - Antiepileptics in Pregnancy

"Use of antiepileptic drugs during pregnancy and risk of spontaneous abortion and stillbirth: population based cohort study"

"Conclusion Among women with epilepsy and when analysing the risk in antiepileptic drug discordant pregnancies in the same woman, we found no overall association between the use of antiepileptic drugs during pregnancy and spontaneous abortions. Therefore unmeasured confounding may explain the slight increased risk for spontaneous abortion with any antiepileptic drug use (among women both with and without epilepsy). We found no association between antiepileptic drug use during pregnancy and stillbirth, but the statistical precision was low."

http://www.bmj.com/content/349/bmj.g5159

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