JAMA: Fluconazole Prophylaxis in Premature Infants

"Effect of Fluconazole Prophylaxis on Candidiasis and Mortality in Premature Infants"
http://jama.jamanetwork.com/article.aspx?articleid=1866096
"Conclusions and Relevance  Among infants with a birth weight of less than 750 g, 42 days of fluconazole prophylaxis compared with placebo did not result in a lower incidence of the composite of death or invasive candidiasis. These findings do not support the universal use of prophylactic fluconazole in extremely low-birth-weight infants."