"Radical Prostatectomy or Watchful Waiting in Early Prostate Cancer"
NEJM
http://www.nejm.org/doi/full/10.1056/NEJMoa1311593 
"CONCLUSIONS

Extended follow-up confirmed a substantial reduction in mortality after radical prostatectomy; the number needed to treat to prevent one death continued to decrease when the treatment was modified according to age at diagnosis and tumor risk. A large proportion of long-term survivors in the watchful-waiting group have not required any palliative treatment. (Funded by the Swedish Cancer Society and others.)"