Tuesday, July 1, 2014

NEJM - Antiretroviral Therapy after Cryptococcal Meningitis


"Timing of Antiretroviral Therapy after Diagnosis of Cryptococcal Meningitis"
http://www.nejm.org/doi/full/10.1056/NEJMoa1312884
"CONCLUSIONS
Deferring ART for 5 weeks after the diagnosis of cryptococcal meningitis was associated with significantly improved survival, as compared with initiating ART at 1 to 2 weeks, especially among patients with a paucity of white cells in cerebrospinal fluid. (Funded by the National Institute of Allergy and Infectious Diseases and others; COAT ClinicalTrials.gov number, NCT01075152.)"

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