"Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data"
http://www.bmj.com/content/349/bmj.g4164
"Conclusions Individuals with a genetic variant associated with non-drinking and lower alcohol consumption had a more favourable cardiovascular profile and a reduced risk of coronary heart disease than those without the genetic variant. This suggests that reduction of alcohol consumption, even for light to moderate drinkers, is beneficial for cardiovascular health."
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