JAMA - Pregnancy Prophylaxis for HIV

"Pregnancy Incidence and Outcomes Among Women Receiving Preexposure Prophylaxis for HIV Prevention"
http://jama.jamanetwork.com/article.aspx?articleid=1889140
"Conclusions and Relevance  Among HIV-serodiscordant heterosexual African couples, differences in pregnancy incidence, birth outcomes, and infant growth were not statistically different for women receiving PrEP with TDF alone or combination FTC+TDF compared with placebo at conception. Given that PrEP was discontinued when pregnancy was detected and that CIs for the birth outcomes were wide, definitive statements about the safety of PrEP in the periconception period cannot be made. These results should be discussed with HIV-uninfected women receiving PrEP who are considering becoming pregnant."