"Colchicine for Prevention of Postpericardiotomy Syndrome and Postoperative Atrial Fibrillation The COPPS-2 Randomized Clinical Trial"
"Conclusions and Relevance Among patients undergoing cardiac surgery, perioperative use of colchicine compared with placebo reduced the incidence of postpericardiotomy syndrome but not of postoperative AF or postoperative pericardial/pleural effusion. The increased risk of gastrointestinal adverse effects reduced the potential benefits of colchicine in this setting."
http://jama.jamanetwork.com/article.aspx?articleid=1900482
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