"A Randomized Trial of Protocol-Based Care for Early Septic Shock"
http://www.nejm.org/doi/full/10.1056/NEJMoa1401602
"CONCLUSIONS
In a multicenter trial conducted in the tertiary care setting, protocol-based resuscitation of patients in whom septic shock was diagnosed in the emergency department did not improve outcomes. (Funded by the National Institute of General Medical Sciences; ProCESS ClinicalTrials.gov number, NCT00510835.)"
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