BMJ - Stroke and Time to TPA

"Time to treatment with recombinant tissue plasminogen activator and outcome of stroke in clinical practice"
http://www.bmj.com/content/348/bmj.g3429
"Conclusion The effectiveness of thrombolytic therapy in daily clinical practice might be comparable with the effectiveness shown in randomised clinical trials and pooled analysis. Early treatment was associated with favourable outcome in daily clinical practice, which underlines the importance of speeding up the process for thrombolytic therapy in hospital and before admission to achieve shorter time from door to needle and from onset to treatment for thrombolytic therapy."