JAMA: Autism - Familial Risk

"The Familial Risk of Autism"
http://jama.jamanetwork.com/article.aspx?articleid=1866100
"Conclusions and Relevance  Among children born in Sweden, the individual risk of ASD and autistic disorder increased with increasing genetic relatedness. Heritability of ASD and autistic disorder were estimated to be approximately 50%. These findings may inform the counseling of families with affected children."  

Weekly Guideline: 2014 AHA PCI Without On-Site Surgery Backup

2014 SCAI / ACC / AHA Update on Percutaneous Corinary Intervention Without On-site Surgerical Backup
http://circ.ahajournals.org/content/early/2014/03/13/CIR.0000000000000037

Circ: Chilhood Obesity & Blood Pressure

"Effect of Childhood Obesity Prevention Programs on Blood Pressure"
http://circ.ahajournals.org/content/129/18/1832.abstract 
"Conclusions—Obesity prevention programs have a moderate effect on reducing BP, and those targeting both diet and physical activity seem to be more effective."

Lancet: Ruptured Aortic Aneurysm Mortality US vs England

"Mortality from ruptured abdominal aortic aneurysms: clinical lessons from a comparison of outcomes in England and the USA"
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(14)60109-4/fulltext
"Interpretation

In-hospital survival from rAAA, intervention rates, and uptake of endovascular repair are lower in England than in the USA. In England and the USA, the lowest mortality for rAAA was seen in teaching hospitals with larger bed capacities and doing a greater proportion of cases with endovascular repair. These common factors suggest strategies for improving outcomes for patients with rAAA." 

NEJM: Septic Shock Protocols

"A Randomized Trial of Protocol-Based Care for Early Septic Shock"  
http://www.nejm.org/doi/full/10.1056/NEJMoa1401602
"CONCLUSIONS

In a multicenter trial conducted in the tertiary care setting, protocol-based resuscitation of patients in whom septic shock was diagnosed in the emergency department did not improve outcomes. (Funded by the National Institute of General Medical Sciences; ProCESS ClinicalTrials.gov number, NCT00510835.)"

JAMA: Fluconazole Prophylaxis in Premature Infants

"Effect of Fluconazole Prophylaxis on Candidiasis and Mortality in Premature Infants"
http://jama.jamanetwork.com/article.aspx?articleid=1866096
"Conclusions and Relevance  Among infants with a birth weight of less than 750 g, 42 days of fluconazole prophylaxis compared with placebo did not result in a lower incidence of the composite of death or invasive candidiasis. These findings do not support the universal use of prophylactic fluconazole in extremely low-birth-weight infants."

Circ: MI Survival with Different Repurfusion Treatments

"Five-Year Survival in Patients With ST-Segment–Elevation Myocardial Infarction According to Modalities of Reperfusion Therapy"
http://circ.ahajournals.org/content/129/16/1629.abstract
"Conclusions—In a real-world setting, on a nationwide scale, a pharmaco-invasive strategy constitutes a valid alternative to pPCI, with 5-year survival at least equivalent to that of the reference reperfusion method."