Tuesday, September 15, 2015

NEJM - "Bivalirudin or Unfractionated Heparin in Acute Coronary Syndromes"

"Bivalirudin or Unfractionated Heparin in Acute Coronary Syndromes"

"RESULTS
The rate of major adverse cardiovascular events was not significantly lower with bivalirudin than with heparin (10.3% and 10.9%, respectively; relative risk, 0.94; 95% confidence interval [CI], 0.81 to 1.09; P=0.44), nor was the rate of net adverse clinical events (11.2% and 12.4%, respectively; relative risk, 0.89; 95% CI, 0.78 to 1.03; P=0.12). Post-PCI bivalirudin infusion, as compared with no infusion, did not significantly decrease the rate of urgent target-vessel revascularization, definite stent thrombosis, or net adverse clinical events (11.0% and 11.9%, respectively; relative risk, 0.91; 95% CI, 0.74 to 1.11; P=0.34)."

http://www.nejm.org/doi/full/10.1056/NEJMoa1507854

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