NEJM - Magnesium for Stroke

"Prehospital Use of Magnesium Sulfate as Neuroprotection in Acute Stroke"  

"CONCLUSIONS   

Prehospital initiation of magnesium sulfate therapy was safe and allowed the start of therapy within 2 hours after the onset of stroke symptoms, but it did not improve disability outcomes at 90 days. (Funded by the National Institute of Neurological Disorders and Stroke; FAST-MAG ClinicalTrials.gov number, NCT00059332.)"  

http://www.nejm.org/doi/full/10.1056/NEJMoa1408827?query=featured_home