CIRC - Nitrate and Exercise Capacity in Heart Failure

"Effect of Inorganic Nitrate on Exercise Capacity in Heart Failure With Preserved Ejection Fraction"

"Conclusions—NO₃⁻ increased exercise capacity in heart failure with preserved ejection fraction by targeting peripheral abnormalities. Efficiency did not change as a result of parallel increases in total work and O_2. NO₃⁻ increased exercise vasodilatory and cardiac output reserves. NO₃⁻ also reduced arterial wave reflections, which are linked to left ventricular diastolic dysfunction and remodeling."  

http://circ.ahajournals.org/content/131/4/371.full