Tuesday, June 17, 2014

NEJM - CPAP & Weight Loss for OSA

"CPAP, Weight Loss, or Both for Obstructive Sleep Apnea"    
http://www.nejm.org/doi/full/10.1056/NEJMoa1306187
"CONCLUSIONS

In adults with obesity and obstructive sleep apnea, CPAP combined with a weight-loss intervention did not reduce CRP levels more than either intervention alone. In secondary analyses, weight loss provided an incremental reduction in insulin resistance and serum triglyceride levels when combined with CPAP. In addition, adherence to a regimen of weight loss and CPAP may result in incremental reductions in blood pressure as compared with either intervention alone. (Funded by the National Heart, Lung, and Blood Institute; ClinicalTrials.gov number, NCT0371293.)"

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