"Intravenous and inhaled MgSO4 for acute asthma"
Lancet May 17
http://www.lancet.com/journals/lanres/article/PIIS2213-2600(13)70097-3/fulltext
"Numerous national and international guidelines exist to guide management of acute asthma.3—5 Most recommend short-acting β-agonists such as salbutamol with metered-dose inhalers or nebulisers,6 short-acting anticholinergics such as ipratropium, and systemic corticosteroids (either by oral or intravenous routes)7 for the treatment of acute asthma. In severe asthma, additional treatment such as intravenous magnesium sulphate (MgSO4),8 inhaled corticosteroids, and epinephrine (intramuscular or nebulised) can be considered. In the most severe cases, clinicians require interventions that reduce the risk of airway complications (ie, intubation), hospital admissions, and other serious sequelae.. . . "