JAMA - Breast Cancer Screening Using Tomosynthesis

 "Breast Cancer Screening Using Tomosynthesis in Combination With Digital Mammography"
http://jama.jamanetwork.com/article.aspx?articleid=1883018
"Conclusions and Relevance  Addition of tomosynthesis to digital mammography was associated with a decrease in recall rate and an increase in cancer detection rate. Further studies are needed to assess the relationship to clinical outcomes."

Weekly Guideline - Pediatric Anthrax

2014 AAP
"Pediatric Anthrax Clinical Management: Executive Summary"
http://pediatrics.aappublications.org/content/133/5/940.full?rss=1

JACC - "Metabolically-Healthy Obesity and Coronary Artery Calcification"

"Metabolically-Healthy Obesity and Coronary Artery Calcification"

"Conclusions  MHO participants had a higher prevalence of subclinical coronary atherosclerosis than metabolically-healthy normal-weight participants, which supports the idea that MHO is not a harmless condition. This association, however, was mediated by metabolic risk factors at levels below those considered abnormal, which suggests that the label of metabolically healthy for obese subjects may be an artifact of the cutoff levels used in the definition of metabolic health."  

JACC June 2014 http://jacc.org/

BMJ - Antidepressant Use in Young People After Warnings

"Changes in antidepressant use by young people and suicidal behavior after FDA warnings and media coverage"

"Conclusions Safety warnings about antidepressants and widespread media coverage decreased antidepressant use, and there were simultaneous increases in suicide attempts among young people. It is essential to monitor and reduce possible unintended consequences of FDA warnings and media reporting."   

http://www.bmj.com/content/348/bmj.g3596

NEJM - Antidepressants & Cardiac Birth Defects

"Antidepressant Use in Pregnancy and the Risk of Cardiac Defects"

"CONCLUSIONS

The results of this large, population-based cohort study suggested no substantial increase in the risk of cardiac malformations attributable to antidepressant use during the first trimester. (Funded by the Agency for Healthcare Research and Quality and the National Institutes of Health.)"   

http://www.nejm.org/doi/full/10.1056/NEJMoa1312828?query=featured_home

JAMA - Thrombolysis for PE Meta-analysis

"Thrombolysis for Pulmonary Embolism and Risk of All-Cause Mortality, Major Bleeding, and Intracranial Hemorrhage A Meta-analysis"

"Conclusions and Relevance  Among patients with pulmonary embolism, including those who were hemodynamically stable with right ventricular dysfunction, thrombolytic therapy was associated with lower rates of all-cause mortality and increased risks of major bleeding and ICH. However, findings may not apply to patients with pulmonary embolism who are hemodynamically stable without right ventricular dysfunction."
http://jama.jamanetwork.com/article.aspx?articleid=1881311

Weekly Guideline - Noninvasive Testing for IHD in Women

"Role of Noninvasive Testing in the Clinical Evaluation of Women With Suspected Ischemic Heart Disease: A Consensus Statement From the American Heart Association"
AHA 2014
http://circ.ahajournals.org/content/early/2014/06/16/CIR.0000000000000061