Wednesday, July 31, 2013

"Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study"
Lancet Jul 26

http://www.thelancet.com/journals/laninf/article/PIIS1473-3099(13)70204-4/fulltext
"Interpretation

Disease caused by MERS-CoV presents with a wide range of clinical manifestations and is associated with substantial mortality in admitted patients who have medical comorbidities. Major gaps in our knowledge of the epidemiology, community prevalence, and clinical spectrum of infection and disease need urgent definition."

Tuesday, July 30, 2013

"Fertility treatment and risk of childhood and adolescent mental disorders: register based cohort study"
BMJ Jul 5
http://www.bmj.com/content/347/bmj.f3978
"Conclusions There was a small increase in the incidence of mental disorders in children born after ovulation induction/intrauterine insemination. Children born after in vitro fertilisation/intracytoplasmic sperm injection were found to have overall risk comparable with children conceived spontaneously."

Monday, July 29, 2013

"Riociguat for the Treatment of Pulmonary Arterial Hypertension"
NEJM Jul 25
http://www.nejm.org/doi/full/10.1056/NEJMoa1209655 
"Riociguat significantly improved exercise capacity and secondary efficacy end points in patients with pulmonary arterial hypertension. (Funded by Bayer HealthCare; . . . "

Sunday, July 28, 2013

"Characteristics Associated With Differences in Survival Among Black and White Women With Breast Cancer" 
JAMA Jul 2013
http://jama.jamanetwork.com/article.aspx?articleid=1719739 
"Conclusions and Relevance  In the SEER-Medicare database, differences in breast cancer survival between black and white women did not substantially change among women diagnosed between 1991 and 2005. These differences in survival appear primarily related to presentation characteristics at diagnosis rather than treatment differences."

Saturday, July 27, 2013

"Alternate-Day, Low-Dose Aspirin and Cancer Risk: Long-Term Observational Follow-up of a Randomized Trial"
Annals Jul 2013
http://annals.org/article.aspx?articleid=1709803 
"Conclusion: Long-term use of alternate-day, low-dose aspirin may reduce risk for colorectal cancer in healthy women."

Friday, July 26, 2013

"Cause of Death Within 30 Days of Percutaneous Coronary Intervention in an Era of Mandatory Outcome Reporting"
Circ Jul 2013
http://content.onlinejacc.org/article.aspx?articleid=1687956
"Conclusions  Less than one-half of 30-day deaths are attributed to a PCI-related complication. Death certificates are inaccurate and do not report PCI-related deaths, which may represent a better marker of PCI quality."

Thursday, July 25, 2013

"Emergency Department Bypass for ST-Segment–Elevation Myocardial Infarction Patients Identified With a Prehospital Electrocardiogram"
JACC Jun 20
http://circ.ahajournals.org/content/128/4/352.full 
"Conclusions—Among ST-segment–elevation myocardial infarction patients identified with a prehospital ECG, the rate of ED bypass varied significantly across US hospitals, but ED bypass occurred infrequently and was mostly isolated to working hours. Because ED bypass was associated with shorter reperfusion times and numerically lower mortality rates, further exploration of and advocacy for the implementation of this process appear warranted."