Saturday, September 7, 2013

"Screening for Peripheral Artery Disease and Cardiovascular Disease Risk Assessment With the Ankle–Brachial Index in Adults: U.S. Preventive Services Task Force Recommendation Statement" 
Annals Sep 3
http://annals.org/article.aspx?articleid=1733279 
"Recommendation: The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for PAD and CVD risk assessment with the ABI in adults."

Friday, September 6, 2013

"Benefits Of Statins In Elderly Subjects Without Established Cardiovascular Disease. A Meta-Analysis"

"Benefits Of Statins In Elderly Subjects Without Established Cardiovascular Disease. A Meta-Analysis"
JACC Aug 2013
http://content.onlinejacc.org/article.aspx?articleid=1732396
"Conclusions  In elderly subjects at high CV risk without established CV disease, statins significantly reduce the incidence of MI and stroke, but do not significantly prolong survival in the short-term."

Thursday, September 5, 2013

"Stent Thrombosis With Ticagrelor Versus Clopidogrel in Patients With Acute Coronary Syndromes"
Circ Jul 30 (online)
http://circ.ahajournals.org/content/128/10/1055.abstract 
"Conclusion—Ticagrelor compared with clopidogrel reduces the incidence of stent thrombosis in patients with acute coronary syndromes, with consistent benefit across a broad range of patient, stent, and treatment characteristics."

Wednesday, September 4, 2013

"Early time-limited antiretroviral therapy versus deferred therapy in South African infants infected with HIV: results from the children with HIV early antiretroviral (CHER) randomised trial"
Lancet Aug 22
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)61409-9/fulltext
"Interpretation
Early time-limited ART had better clinical and immunological outcomes than deferred ART, with no evidence of excess disease progression during subsequent treatment interruption and less overall ART exposure than deferred ART. Longer time on primary ART permits longer subsequent interruption, with marginally better outcomes"

Tuesday, September 3, 2013

"Fruit consumption and risk of type 2 diabetes: results from three prospective longitudinal cohort studies"
BMJ Aug 29
http://ww w.bmj.com/content/347/bmj.f5001 
"Conclusion Our findings suggest the presence of heterogeneity in the associations between individual fruit consumption and risk of type 2 diabetes. Greater consumption of specific whole fruits, particularly blueberries, grapes, and apples, is significantly associated with a lower risk of type 2 diabetes, whereas greater consumption of fruit juice is associated with a higher risk."

Monday, September 2, 2013

"Dabigatran versus Warfarin in Patients with Mechanical Heart Valves"
NEJM Sep 1
http://www.nejm.org/doi/full/10.1056/NEJMoa1300615?query=featured_home
"CONCLUSIONS
The use of dabigatran in patients with mechanical heart valves was associated with increased rates of thromboembolic and bleeding complications, as compared with warfarin, thus showing no benefit and an excess risk."

Sunday, September 1, 2013

"Association Between Cholecystectomy With vs Without Intraoperative Cholangiography and Risk of Common Duct Injury"JAMA Aug 28
http://jama.jamanetwork.com/article.aspx?articleid=1733717 
"Conclusions and Relevance   When confounders were controlled with instrumental variable analysis, there was no statistically significant association between intraoperative cholangiography and common duct injury. Intraoperative cholangiography is not effective as a preventive strategy against common duct injury during cholecystectomy."