Saturday, December 31, 2016
Wednesday, June 1, 2016
Research June 2016
ANNALS
"Variability in Pathologists' Interpretations of Individual Breast Biopsy Slides: A Population Perspective"
"Conclusion:
This analysis, based on interpretation of a single breast biopsy slide per case, predicts a low likelihood that a diagnosis of atypia or DCIS would be verified by a reference consensus diagnosis. This diagnostic grey zone should be considered in clinical management decisions in patients with these diagnoses."
http://annals.org/article.aspx?articleid=2505396
BMJ / Lancet
"One versus two years of elastic compression stockings for prevention of post-thrombotic syndrome (OCTAVIA study): randomised controlled trial"
"Conclusion
Stopping ECS after one year in compliant patients with proximal deep venous thrombosis seemed not to be non-inferior to continuing ECS therapy for two years in this non-inferiority trial."
http://www.bmj.com/content/353/bmj.i2691
CIRC / JACC
"Prepregnancy Diabetes and Offspring Risk of Congenital Heart Disease"
http://circ.ahajournals.org/content/133/23/2243.full
JAMA
"Effect of Dilute Apple Juice and Preferred Fluids vs Electrolyte Maintenance Solution on Treatment Failure Among Children With Mild Gastroenteritis"
"Conclusions and Relevance
Among children with mild gastroenteritis and minimal dehydration, initial oral hydration with dilute apple juice followed by their preferred fluids, compared with electrolyte maintenance solution, resulted in fewer treatment failures. In many high-income countries, the use of dilute apple juice and preferred fluids as desired may be an appropriate alternative to electrolyte maintenance fluids in children with mild gastroenteritis and minimal dehydration."
http://jama.jamanetwork.com/article.aspx?articleid=2518402
NEJM
"Cryoballoon or Radiofrequency Ablation for Paroxysmal Atrial Fibrillation"
http://www.nejm.org/doi/full/10.1056/NEJMoa1602014?query=featured_home
"Variability in Pathologists' Interpretations of Individual Breast Biopsy Slides: A Population Perspective"
"Conclusion:
This analysis, based on interpretation of a single breast biopsy slide per case, predicts a low likelihood that a diagnosis of atypia or DCIS would be verified by a reference consensus diagnosis. This diagnostic grey zone should be considered in clinical management decisions in patients with these diagnoses."
http://annals.org/article.aspx?articleid=2505396
BMJ / Lancet
"One versus two years of elastic compression stockings for prevention of post-thrombotic syndrome (OCTAVIA study): randomised controlled trial"
"Conclusion
Stopping ECS after one year in compliant patients with proximal deep venous thrombosis seemed not to be non-inferior to continuing ECS therapy for two years in this non-inferiority trial."
http://www.bmj.com/content/353/bmj.i2691
CIRC / JACC
"Prepregnancy Diabetes and Offspring Risk of Congenital Heart Disease"
http://circ.ahajournals.org/content/133/23/2243.full
JAMA
"Effect of Dilute Apple Juice and Preferred Fluids vs Electrolyte Maintenance Solution on Treatment Failure Among Children With Mild Gastroenteritis"
"Conclusions and Relevance
Among children with mild gastroenteritis and minimal dehydration, initial oral hydration with dilute apple juice followed by their preferred fluids, compared with electrolyte maintenance solution, resulted in fewer treatment failures. In many high-income countries, the use of dilute apple juice and preferred fluids as desired may be an appropriate alternative to electrolyte maintenance fluids in children with mild gastroenteritis and minimal dehydration."
http://jama.jamanetwork.com/article.aspx?articleid=2518402
NEJM
"Cryoballoon or Radiofrequency Ablation for Paroxysmal Atrial Fibrillation"
http://www.nejm.org/doi/full/10.1056/NEJMoa1602014?query=featured_home
Sunday, May 1, 2016
Research May 2016
ANNALS
"Gradual Versus Abrupt Smoking Cessation: A Randomized, Controlled Noninferiority Trial"
http://annals.org/article.aspx?articleid=2501853
"Long-Term Risk for Device-Related Complications and Reoperations After Implantable Cardioverter-Defibrillator Implantation"
http://annals.org/article.aspx?articleid=2520465
BMJ
"BMI and all cause mortality: systematic review and non-linear dose-response meta-analysis of 230 cohort studies with 3.74 million deaths among 30.3 million participants"
http://www.bmj.com/content/353/bmj.i2156
"Effect of age and sex on efficacy and tolerability of β blockers in patients with heart failure with reduced ejection fraction: individual patient data meta-analysis"
"Conclusion
Irrespective of age or sex, patients with HFrEF in sinus rhythm should receive β blockers to reduce the risk of death and admission to hospital."
http://www.bmj.com/content/353/bmj.i1855
CIRC / JACC
"Reduced Cardiac Index Is Not the Dominant Driver of Renal Dysfunction in Heart Failure"
http://content.onlinejacc.org/article.aspx?articleID=2520902
"Diabetes Mellitus and Prevention of Late Myocardial Infarction After Coronary Stenting in the Randomized Dual Antiplatelet Therapy Study"
http://circ.ahajournals.org/content/133/18/1772.full
JAMA
"Effect of Using the Same vs Different Order for Second Readings of Screening Mammograms on Rates of Breast Cancer Detection"
"Conclusions and Relevance Interpretation of batches of mammograms by qualified screening mammography readers using a different order vs the same order for the second reading resulted in no significant difference in rates of detection of breast cancer."
http://jama.jamanetwork.com/article.aspx?articleid=2520628
"Prevalence of Inappropriate Antibiotic Prescriptions Among US Ambulatory Care Visits, 2010-2011"
http://jama.jamanetwork.com/article.aspx?articleid=2518263
NEJM
"Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest"
http://www.nejm.org/doi/full/10.1056/NEJMoa1514204?query=featured_home
"Initiation Strategies for Renal-Replacement Therapy in the Intensive Care Unit'
http://www.nejm.org/doi/full/10.1056/NEJMoa1603017?query=featured_home
"Gradual Versus Abrupt Smoking Cessation: A Randomized, Controlled Noninferiority Trial"
http://annals.org/article.aspx?articleid=2501853
"Long-Term Risk for Device-Related Complications and Reoperations After Implantable Cardioverter-Defibrillator Implantation"
http://annals.org/article.aspx?articleid=2520465
BMJ
"BMI and all cause mortality: systematic review and non-linear dose-response meta-analysis of 230 cohort studies with 3.74 million deaths among 30.3 million participants"
http://www.bmj.com/content/353/bmj.i2156
"Effect of age and sex on efficacy and tolerability of β blockers in patients with heart failure with reduced ejection fraction: individual patient data meta-analysis"
"Conclusion
Irrespective of age or sex, patients with HFrEF in sinus rhythm should receive β blockers to reduce the risk of death and admission to hospital."
http://www.bmj.com/content/353/bmj.i1855
CIRC / JACC
"Reduced Cardiac Index Is Not the Dominant Driver of Renal Dysfunction in Heart Failure"
http://content.onlinejacc.org/article.aspx?articleID=2520902
"Diabetes Mellitus and Prevention of Late Myocardial Infarction After Coronary Stenting in the Randomized Dual Antiplatelet Therapy Study"
http://circ.ahajournals.org/content/133/18/1772.full
JAMA
"Effect of Using the Same vs Different Order for Second Readings of Screening Mammograms on Rates of Breast Cancer Detection"
"Conclusions and Relevance Interpretation of batches of mammograms by qualified screening mammography readers using a different order vs the same order for the second reading resulted in no significant difference in rates of detection of breast cancer."
http://jama.jamanetwork.com/article.aspx?articleid=2520628
"Prevalence of Inappropriate Antibiotic Prescriptions Among US Ambulatory Care Visits, 2010-2011"
http://jama.jamanetwork.com/article.aspx?articleid=2518263
NEJM
"Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest"
http://www.nejm.org/doi/full/10.1056/NEJMoa1514204?query=featured_home
"Initiation Strategies for Renal-Replacement Therapy in the Intensive Care Unit'
http://www.nejm.org/doi/full/10.1056/NEJMoa1603017?query=featured_home
Guidelines May 2016
May 26, 2016
"2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease"
http://circ.ahajournals.org/content/early/2016/03/28/CIR.0000000000000404
"Duration of Dual Antiplatelet Therapy: A Systematic Review for the 2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease"
http://circ.ahajournals.org/content/early/2016/03/28/CIR.0000000000000405
--------------
May 19, 2016
"Appropriate Antibiotic Use for Acute Respiratory Tract Infection in Adults: Advice for High-Value Care From the American College of Physicians and the Centers for Disease Control and Prevention"
http://annals.org/article.aspx?articleid=2481815
---------------
May 12, 2016
"Aspirin Use for the Primary Prevention of Cardiovascular Disease and Colorectal Cancer: U.S. Preventive Services Task Force Recommendation Statement"
http://annals.org/article.aspx?articleid=2513179
--------------
May 5, 2016
"AHA Scientific Statement Electrocardiographic Early Repolarization"
http://circ.ahajournals.org/content/133/15/1520.full
"The early repolarization (ER) pattern (ERP), initially described as elevation of the ST segment of ≥1 leads on the 12-lead ECG, has long been considered a benign phenomenon. However, more recent studies have demonstrated positive, negative, and neutral associations between an ERP and various end points, including all-cause, cardiac, and arrhythmic mortality. These recent studies have used more complex or heterogeneous definitions of ER, including J-wave or J-point elevation and QRS complex notching or slurring, with or without concomitant ST-segment elevation. Other studies have identified an increased prevalence of ERP in survivors of spontaneous ventricular fibrillation (VF) or cardiac arrest."
"2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease"
http://circ.ahajournals.org/content/early/2016/03/28/CIR.0000000000000404
"Duration of Dual Antiplatelet Therapy: A Systematic Review for the 2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease"
http://circ.ahajournals.org/content/early/2016/03/28/CIR.0000000000000405
--------------
May 19, 2016
"Appropriate Antibiotic Use for Acute Respiratory Tract Infection in Adults: Advice for High-Value Care From the American College of Physicians and the Centers for Disease Control and Prevention"
http://annals.org/article.aspx?articleid=2481815
---------------
May 12, 2016
"Aspirin Use for the Primary Prevention of Cardiovascular Disease and Colorectal Cancer: U.S. Preventive Services Task Force Recommendation Statement"
http://annals.org/article.aspx?articleid=2513179
--------------
May 5, 2016
"AHA Scientific Statement Electrocardiographic Early Repolarization"
http://circ.ahajournals.org/content/133/15/1520.full
"The early repolarization (ER) pattern (ERP), initially described as elevation of the ST segment of ≥1 leads on the 12-lead ECG, has long been considered a benign phenomenon. However, more recent studies have demonstrated positive, negative, and neutral associations between an ERP and various end points, including all-cause, cardiac, and arrhythmic mortality. These recent studies have used more complex or heterogeneous definitions of ER, including J-wave or J-point elevation and QRS complex notching or slurring, with or without concomitant ST-segment elevation. Other studies have identified an increased prevalence of ERP in survivors of spontaneous ventricular fibrillation (VF) or cardiac arrest."
Friday, April 1, 2016
Research Review April 2016
ANNALS:
"The Effect of Erythropoietin-Stimulating Agents on Health-Related Quality of Life in Anemia of Chronic Kidney Disease: A Systematic Review and Meta-analysis"
http://annals.org/article.aspx?articleid=2491918
"Relationship Among Body Fat Percentage, Body Mass Index, and All-Cause Mortality: A Cohort Study" http://annals.org/article.aspx?articleid=2499472
====================================================
BMJ:
"Methotrexate monotherapy and methotrexate combination therapy with traditional and biologic disease modifying antirheumatic drugs for rheumatoid arthritis: abridged Cochrane systematic review and network meta-analysis"
http://www.bmj.com/content/353/bmj.i1777
"Defibrillation time intervals and outcomes of cardiac arrest in hospital: retrospective cohort study from Get With The Guidelines-Resuscitation registry"
http://www.bmj.com/content/353/bmj.i1653
====================================================
CIRC:
REVIEW:
"Peripartum Cardiomyopathy"
http://circ.ahajournals.org/content/133/14/1397.full
"Individualized Statin Benefit for Determining Statin Eligibility in the Primary Prevention of Cardiovascular Disease"
http://circ.ahajournals.org/content/133/16/1574.abstract
====================================================
JAMA:
"Effect of Postextubation High-Flow Nasal Cannula vs Conventional Oxygen Therapy on Reintubation in Low-Risk Patients"
https://jama.jamanetwork.com/article.aspx?articleid=2503420
"Effect of Losmapimod on Cardiovascular Outcomes in Patients Hospitalized With Acute Myocardial Infarction"
https://jama.jamanetwork.com/article.aspx?articleid=2511223
====================================================
NEJM:
"Fresh Fruit Consumption and Major Cardiovascular Disease in China" http://www.nejm.org/doi/full/10.1056/NEJMoa1501451
"CONCLUSIONS Among Chinese adults, a higher level of fruit consumption was associated with lower blood pressure and blood glucose levels and, largely independent of these and other dietary and nondietary factors, with significantly lower risks of major cardiovascular diseases. "
"Aliskiren, Enalapril, or Aliskiren and Enalapril in Heart Failure" http://www.nejm.org/doi/full/10.1056/NEJMoa1514859
"CONCLUSIONS In patients with chronic heart failure, the addition of aliskiren to enalapril led to more adverse events without an increase in benefit. Noninferiority was not shown for aliskiren as compared with enalapril. (Funded by Novartis; ATMOSPHERE ClinicalTrials.gov number,NCT00853658.)"
"The Effect of Erythropoietin-Stimulating Agents on Health-Related Quality of Life in Anemia of Chronic Kidney Disease: A Systematic Review and Meta-analysis"
http://annals.org/article.aspx?articleid=2491918
"Relationship Among Body Fat Percentage, Body Mass Index, and All-Cause Mortality: A Cohort Study" http://annals.org/article.aspx?articleid=2499472
====================================================
BMJ:
"Methotrexate monotherapy and methotrexate combination therapy with traditional and biologic disease modifying antirheumatic drugs for rheumatoid arthritis: abridged Cochrane systematic review and network meta-analysis"
http://www.bmj.com/content/353/bmj.i1777
"Defibrillation time intervals and outcomes of cardiac arrest in hospital: retrospective cohort study from Get With The Guidelines-Resuscitation registry"
http://www.bmj.com/content/353/bmj.i1653
====================================================
CIRC:
REVIEW:
"Peripartum Cardiomyopathy"
http://circ.ahajournals.org/content/133/14/1397.full
"Individualized Statin Benefit for Determining Statin Eligibility in the Primary Prevention of Cardiovascular Disease"
http://circ.ahajournals.org/content/133/16/1574.abstract
====================================================
JAMA:
"Effect of Postextubation High-Flow Nasal Cannula vs Conventional Oxygen Therapy on Reintubation in Low-Risk Patients"
https://jama.jamanetwork.com/article.aspx?articleid=2503420
"Effect of Losmapimod on Cardiovascular Outcomes in Patients Hospitalized With Acute Myocardial Infarction"
https://jama.jamanetwork.com/article.aspx?articleid=2511223
====================================================
NEJM:
"Fresh Fruit Consumption and Major Cardiovascular Disease in China" http://www.nejm.org/doi/full/10.1056/NEJMoa1501451
"CONCLUSIONS Among Chinese adults, a higher level of fruit consumption was associated with lower blood pressure and blood glucose levels and, largely independent of these and other dietary and nondietary factors, with significantly lower risks of major cardiovascular diseases. "
"Aliskiren, Enalapril, or Aliskiren and Enalapril in Heart Failure" http://www.nejm.org/doi/full/10.1056/NEJMoa1514859
"CONCLUSIONS In patients with chronic heart failure, the addition of aliskiren to enalapril led to more adverse events without an increase in benefit. Noninferiority was not shown for aliskiren as compared with enalapril. (Funded by Novartis; ATMOSPHERE ClinicalTrials.gov number,NCT00853658.)"
Guidelines April 2016
April 29, 2016
"AHA Scientific Statement Acute Myocardial Infarction in Women
A Scientific Statement From the American Heart Association"
http://circ.ahajournals.org/content/133/9/916
---------------
April 22, 2016
"Diagnosis and Management of Diabetes: Synopsis of the 2016 American Diabetes Association Standards of Medical Care in Diabetes"
http://annals.org/article.aspx?articleid=2498492
--------------
April 15, 2016
"Hematuria as a Marker of Occult Urinary Tract Cancer: Advice for High-Value Care From the American College of Physicians"
http://annals.org/article.aspx?articleid=2484287
--------------
April 8, 2016
"2015 International Consensus on First Aid Science With Treatment Recommendations
Part 9: First Aid"
http://circ.ahajournals.org/content/132/16_suppl_1/S269.full
--------------
April 1, 2016
"2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations
Part 8: Education, Implementation, and Teams"
http://circ.ahajournals.org/content/132/16_suppl_1/S242.full
"AHA Scientific Statement Acute Myocardial Infarction in Women
A Scientific Statement From the American Heart Association"
http://circ.ahajournals.org/content/133/9/916
---------------
April 22, 2016
"Diagnosis and Management of Diabetes: Synopsis of the 2016 American Diabetes Association Standards of Medical Care in Diabetes"
http://annals.org/article.aspx?articleid=2498492
--------------
April 15, 2016
"Hematuria as a Marker of Occult Urinary Tract Cancer: Advice for High-Value Care From the American College of Physicians"
http://annals.org/article.aspx?articleid=2484287
--------------
April 8, 2016
"2015 International Consensus on First Aid Science With Treatment Recommendations
Part 9: First Aid"
http://circ.ahajournals.org/content/132/16_suppl_1/S269.full
--------------
April 1, 2016
"2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations
Part 8: Education, Implementation, and Teams"
http://circ.ahajournals.org/content/132/16_suppl_1/S242.full
Tuesday, March 1, 2016
Guidelines March 2016
Dates reflect the EvidMed listing date, not the guideline publication date
March 25, 2016
"2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations
Part 7: Neonatal Resuscitation"
http://circ.ahajournals.org/content/132/16_suppl_1/S204.full
-----------------
March 18, 2016
March 11, 2016:
"2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations
Part 5: Acute Coronary Syndromes"
http://circ.ahajournals.org/content/132/16_suppl_1/S146.full
-------------------
March 4, 2016:
"2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations
Part 4: Advanced Life Support"
http://circ.ahajournals.org/content/132/16_suppl_1/S84.full
March 25, 2016
"2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations
Part 7: Neonatal Resuscitation"
http://circ.ahajournals.org/content/132/16_suppl_1/S204.full
-----------------
March 18, 2016
"2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations
Part 6: Pediatric Basic Life Support and Pediatric Advanced Life Support"
http://circ.ahajournals.org/content/132/16_suppl_1/S177.full
------------------Part 6: Pediatric Basic Life Support and Pediatric Advanced Life Support"
http://circ.ahajournals.org/content/132/16_suppl_1/S177.full
March 11, 2016:
"2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations
Part 5: Acute Coronary Syndromes"
http://circ.ahajournals.org/content/132/16_suppl_1/S146.full
-------------------
March 4, 2016:
"2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations
Part 4: Advanced Life Support"
http://circ.ahajournals.org/content/132/16_suppl_1/S84.full
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